Table I. Comparison of MAVS-deficient mouse models used in this study
DesignationMutation LocationProtein Expression?Genetic BackgroundOriginal Ref.
B6/129.MAVSKOExons 2 and 3AbsentB6/129 F2Sun et al. 2006 (17)
B6.MAVSKOExons 1 and 2AbsentBackcrossed to 99.6% B6Kumar et al. 2006 (19)