Table I.
Comparison of MAVS-deficient mouse models used in this study
Designation
Mutation Location
Protein Expression?
Genetic Background
Original Ref.
B6/129.MAVSKO
Exons 2 and 3
Absent
B6/129 F2
Sun et al. 2006 (
17
)
B6.MAVSKO
Exons 1 and 2
Absent
Backcrossed to 99.6% B6
Kumar et al. 2006 (
19
)