Table I. Select genes altered by AhR activation in DCs during IAV infection
Gene NameLog2-Fold Change (TCDD/Vehicle)p Value
Ahrr3.8741.25 × 10−123
Cyp1a12.4158.29 × 10−20
Nos21.5708.86 × 10−43
Clec4d1.2542.07 × 10−22
Ido11.2383.07 × 10−7
Clec4a40.9905.20 × 10−6
Il100.8092.35 × 10−4
Cd2740.7376.75 × 10−9
Cxcl30.6584.34 × 10−10
Cxcl160.6164.66 × 10−10
Clec7a−0.6661.29 × 10−7
Ccl6−0.7176.82 × 10−4
Ccl9−0.7902.02 × 10−6
Pdcd1−0.8463.27 × 10−3
Arg1−0.9241.57 × 10−6
Ccl22−1.0292.68 × 10−7
Clec4m−1.2181.08 × 10−9
Cd209d−1.2816.02 × 10−7
Cd209a−1.3372.88 × 10−6
Ccl17−1.7422.88 × 10−6
  • Log2 (fold change) and p value of 10 upregulated and 10 downregulated genes of interest expressed in DCs from infected mice following AhR activation.