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Open Access

TLR7 and TLR8 Differentially Activate the IRF and NF-κB Pathways in Specific Cell Types to Promote Inflammation

Andrew T. Bender, Evgeni Tzvetkov, Albertina Pereira, Yin Wu, Siddha Kasar, Melinda M. Przetak, Jaromir Vlach, Timothy B. Niewold, Mark A. Jensen and Shinji L. Okitsu
ImmunoHorizons February 1, 2020, 4 (2) 93-107; DOI: https://doi.org/10.4049/immunohorizons.2000002
Andrew T. Bender
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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Evgeni Tzvetkov
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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Albertina Pereira
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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  • ORCID record for Albertina Pereira
Yin Wu
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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Siddha Kasar
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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Melinda M. Przetak
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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Jaromir Vlach
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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  • ORCID record for Jaromir Vlach
Timothy B. Niewold
†Colton Center for Autoimmunity, New York University School of Medicine, New York, NY 10016
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Mark A. Jensen
†Colton Center for Autoimmunity, New York University School of Medicine, New York, NY 10016
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Shinji L. Okitsu
*Immunology, EMD Serono Research and Development Institute, Billerica, MA 01821; and
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Online ISSN 2573-7732