TSC1 Suppresses Macrophage Necroptosis for the Control of Infection by Fungal Pathogen Candida albicans

*Ear, Nose, and Throat Institute and Department of Otorhinolaryngology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 200031 Shanghai, China;

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

*Ear, Nose, and Throat Institute and Department of Otorhinolaryngology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 200031 Shanghai, China;

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

‡School of Life Sciences, Lanzhou University, Lanzhou, Gansu 730000, China;

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;

§Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China; and

*Ear, Nose, and Throat Institute and Department of Otorhinolaryngology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 200031 Shanghai, China;

‡School of Life Sciences, Lanzhou University, Lanzhou, Gansu 730000, China;

¶Marine Drug Screening and Evaluation Platform, Qingdao National Laboratory for Marine Science and Technology, Ocean University of China, Qingdao, 266071 Shandong, China

†The Center for Microbes, Development and Health, Chinese Academy of Sciences, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China;